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Trial NCT00957710

Resource URI: http://static.linkedct.org/resource/trials/NCT00957710
PropertyValue
linkedct:arm_group <http://static.linkedct.org/resource/arm_group/51364>
linkedct:brief_title Language Treatment for Progressive Aphasia
linkedct:collaborator_agency <http://static.linkedct.org/resource/collabagency/1060>
linkedct:condition <http://static.linkedct.org/resource/condition/10738>
linkedct:condition <http://static.linkedct.org/resource/condition/11928>
linkedct:condition <http://static.linkedct.org/resource/condition/16534>
linkedct:criteria Inclusion Criteria: - Diagnosis of progressive aphasia - Native English speaker or fluent in English - Adequate hearing and vision (not requiring more than +6 diopter correction) - Willing and able to participate in each phase of the study (including two fMRI sessions) Exclusion Criteria: - Contraindications to fMRI (e.g., claustrophobia, pacemaker, ferromagnetic implant) - Current medical or psychiatric condition affecting cognition (other than progressive aphasia)
linkedct:download_date Information obtained from ClinicalTrials.gov on December 30, 2009
linkedct:eligibility_gender Both
linkedct:eligibility_healthy_volunteers Accepts Healthy Volunteers
linkedct:eligibility_maximum_age 80 Years
linkedct:eligibility_minimum_age 40 Years
linkedct:end_date December 2010
linkedct:enrollment 14 (xsd:int)
linkedct:firstreceived_date August 11, 2009
linkedct:has_dmc No
linkedct:id NCT00957710
linkedct:intervention <http://static.linkedct.org/resource/intervention/82461>
rdfs:label Trial NCT00957710
linkedct:lastchanged_date August 11, 2009
linkedct:lead_sponsor_agency Baycrest
linkedct:location <http://static.linkedct.org/resource/location/20728>
linkedct:nct_id NCT00957710
linkedct:number_of_arms 1 (xsd:int)
linkedct:number_of_groups 0 (xsd:int)
linkedct:official_title Slowing Language Decline in Progressive Aphasia Through Language Rehabilitation: Treatment and Neuroimaging Study
linkedct:org_study_id REB 09-24
linkedct:overall_contact_email achaudry@utoronto.ca
linkedct:overall_contact_last_name Anoosh Chaudry
linkedct:overall_contact_phone 416 785-2500
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/49184>
linkedct:overall_status Recruiting
linkedct:oversight <http://static.linkedct.org/resource/oversight/402>
linkedct:oversight <http://static.linkedct.org/resource/oversight/410>
foaf:page <http://clinicaltrials.gov/show/NCT00957710>
linkedct:phase N/A
linkedct:primary_completion_date July 2010
linkedct:primary_outcomes <http://static.linkedct.org/resource/primary_outcomes/39866>
linkedct:reference <http://static.linkedct.org/resource/reference/1818>
linkedct:reference <http://static.linkedct.org/resource/reference/23065>
linkedct:reference <http://static.linkedct.org/resource/reference/31475>
linkedct:reference <http://static.linkedct.org/resource/reference/37541>
linkedct:secondary_outcomes <http://static.linkedct.org/resource/secondary_outcomes/26208>
linkedct:source Baycrest
linkedct:start_date August 2009
linkedct:study_design Other, Non-Randomized, Open Label, Parallel Assignment
linkedct:study_type Interventional
linkedct:summary Progressive aphasia is characterized by a steady and progressive loss of language skills in the presence of relatively preserved memory, attention, and thinking. The aim of this study is to slow the progression of language decline in progressive aphasia via language therapy. The first goal of this study is to improve naming abilities of individuals with progressive aphasia. This will be accomplished by carrying out an intensive treatment program for anomia. The second goal is to evaluate whether this intense language treatment re-activates affected areas and/or connections within the language network, using functional Magnetic Resonance Imaging (to measure neural activity in specific brain regions) and Diffusion Tensor Imaging tractography (to measure the connectivity between specific brain regions). This is the first study on progressive aphasia addressing both treatment and imaging in the same patients.
rdf:type linkedct:trials
linkedct:verification_date August 2009