Home | All trials

[RDF data]
Trial NCT00484250

Resource URI: http://static.linkedct.org/resource/trials/NCT00484250
linkedct:brief_title Study of Metronidazole and Doxycycline to Treat Oral Lichen Planus and to Compare Their Efficacy With Each Other
linkedct:condition <http://static.linkedct.org/resource/condition/9290>
linkedct:criteria Inclusion Criteria: - a biopsy-proven untreated OLP of every type with no symptom. Exclusion Criteria: - pregnancy, presence of dysplasia in lesions,unilateral lesion suspected lichenoid reaction,history of drinking alcohol in at least 1 month prior to the study, smoking, systemic disease, use of systemic medications and hypersensitivity to the metronidazole and doxycycline.
linkedct:download_date Information obtained from ClinicalTrials.gov on December 30, 2009
linkedct:eligibility_gender Both
linkedct:eligibility_healthy_volunteers No
linkedct:eligibility_maximum_age N/A
linkedct:eligibility_minimum_age N/A
linkedct:end_date May 2006
linkedct:enrollment 20 (xsd:int)
linkedct:firstreceived_date June 7, 2007
linkedct:has_dmc Yes
linkedct:id NCT00484250
rdfs:label Trial NCT00484250
linkedct:lastchanged_date June 8, 2007
linkedct:lead_sponsor_agency Mashhad University of Medical Sciences
linkedct:location <http://static.linkedct.org/resource/location/73101>
linkedct:nct_id NCT00484250
linkedct:number_of_arms 0 (xsd:int)
linkedct:number_of_groups 0 (xsd:int)
linkedct:org_study_id 240
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/17567>
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/36701>
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/4043>
linkedct:overall_status Completed
linkedct:oversight <http://static.linkedct.org/resource/oversight/1388>
foaf:page <http://clinicaltrials.gov/show/NCT00484250>
linkedct:phase Phase 2
linkedct:source Mashhad University of Medical Sciences
linkedct:start_date September 2005
linkedct:study_design Treatment, Randomized, Double-Blind, Active Control, Parallel Assignment, Efficacy Study
linkedct:study_type Interventional
linkedct:summary Oral lichen planus (OLP) is a chronic inflammatory disorder which causes local irritation,discomfort and subsequent poor dentition and discomfort in eating . Various treatments have been suggested for OLP but their results are unsatisfactory .Despite the fact that steroids have been the main therapeutic choice for many years,some researches have been done regarding the efficacy of other medication such as metronidazole and doxycycline.The purpose of this study is to determine whether metronidazole and doxycycline are effective in the treatment of oral lichen planus and to compare their efficacy with each other.
rdf:type linkedct:trials
linkedct:verification_date June 2007