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Trial NCT00477061

Resource URI: http://static.linkedct.org/resource/trials/NCT00477061
linkedct:brief_title Morphine Analgesia in Patients With Acute Appendicitis
linkedct:condition <http://static.linkedct.org/resource/condition/1144>
linkedct:criteria Inclusion Criteria: - clinical signs of acute appendicitis - planned for appendectomy - supposed to wait for at least 1 hour in the ED before operation Exclusion Criteria: - suspicion to perforated appendicitis - being under the age of 13 - pregnancy (according to history and ß-HCG result) - opium addiction - systolic blood pressure of less than 90 mmHG - known cases of chronic obstructive pulmonary disease (COPD) - known sensitivity to morphine - history of sickle cell disease - self administration of analgesics before enrollment - refusal to participate
linkedct:description Analgesic administration for pain control in patients with acute abdominal pain, regarding acute appendicitis, is controversial. Despite the results previous studies indicating the safeness of analgesic use in ED for acute abdominal pain, physicians still prefer to postpone their use after performing surgical evaluations. Since many patients admitted to ED are unlikely to receive prompt surgical consultation, many of them need pain relief to prevent unnecessary suffering. On the other hand such pain relief must not interfere with the diagnosis and treatment of patients and do not cause any complications. Morphine is a common and effective analgesic which, if shown to have no effect on correct diagnosis of acute abdomen, can be used for this purpose. Thus we evaluated morphine effect on pain reduction and diagnostic accuracy in patients admitted to ED with the diagnosis of acute appendicitis.
linkedct:download_date Information obtained from ClinicalTrials.gov on December 30, 2009
linkedct:eligibility_gender Both
linkedct:eligibility_healthy_volunteers No
linkedct:eligibility_maximum_age 75 Years
linkedct:eligibility_minimum_age 13 Years
linkedct:end_date March 2005
linkedct:enrollment 71 (xsd:int)
linkedct:firstreceived_date May 20, 2007
linkedct:has_dmc No
linkedct:id NCT00477061
rdfs:label Trial NCT00477061
linkedct:lastchanged_date May 20, 2007
linkedct:lead_sponsor_agency Tehran University of Medical Sciences
linkedct:location <http://static.linkedct.org/resource/location/73007>
linkedct:nct_id NCT00477061
linkedct:number_of_arms 2 (xsd:int)
linkedct:number_of_groups 0 (xsd:int)
linkedct:official_title Double Blind Randomized Study of Morphine Analgesia in Patients With Acute Appendicitis
linkedct:org_study_id AG11
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/4515>
linkedct:overall_status Completed
linkedct:oversight <http://static.linkedct.org/resource/oversight/1388>
foaf:page <http://clinicaltrials.gov/show/NCT00477061>
linkedct:phase Phase 4
linkedct:primary_outcomes <http://static.linkedct.org/resource/primary_outcomes/15142>
linkedct:secondary_outcomes <http://static.linkedct.org/resource/secondary_outcomes/36443>
linkedct:source Tehran University of Medical Sciences
linkedct:start_date January 2004
linkedct:study_design Supportive Care, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study
linkedct:study_type Interventional
linkedct:summary The purpose of the study is to evaluate morphine effect on pain reduction and diagnostic accuracy in patients admitted to emergency ward with the diagnosis of acute appendicitis.
rdf:type linkedct:trials
linkedct:verification_date May 2007