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Trial NCT00434460

Resource URI: http://static.linkedct.org/resource/trials/NCT00434460
PropertyValue
linkedct:acronym ABATEVAP
linkedct:arm_group <http://static.linkedct.org/resource/arm_group/8651>
linkedct:biospec_retention None Retained
linkedct:brief_title Study of Knowledge Translation of Clinical Practice Guidelines for Ventilator Associated Pneumonia
linkedct:collaborator_agency <http://static.linkedct.org/resource/collabagency/1060>
linkedct:collaborator_agency <http://static.linkedct.org/resource/collabagency/4400>
linkedct:collaborator_agency <http://static.linkedct.org/resource/collabagency/533>
linkedct:collaborator_agency <http://static.linkedct.org/resource/collabagency/688>
linkedct:condition <http://static.linkedct.org/resource/condition/13734>
linkedct:criteria Inclusion Criteria: - Age >= 17 years old - Mechanically ventilated > 48 hours < 96 hours Exclusion Criteria: - Previous enrollment in the study
linkedct:description Background: In order to improve the care of our patients, it is necessary for research evidence to be translated into clinical practice. There are gaps in our understanding of knowledge translation (KT) and this is evident in the Intensive Care Unit (ICU), specifically as it applies to the prevention, diagnosis and treatment of ventilator-associated pneumonia (VAP). VAP is associated with a high burden of illness in the critically ill and there is an extensive amount of research evidence on this disease. It has been demonstrated that best practice as defined by research evidence is not uniformly applied to VAP. In addition, recent advances in VAP knowledge need be disseminated and implemented in order to improve patient safety and outcomes from VAP. A systematic process of knowledge transfer is crucial to translate this research into evidence-based bedside practice and the development and implementation of evidence based Clinical Practice Guidelines (CPGs) may facilitate VAP knowledge uptake. In addition, there is a need to study knowledge translation (KT) in the ICU since there is little information about optimal KT and CPG implementation strategies in this environment and efforts that are effective in other clinical areas may not result in meaningful change in the ICU. Research Question: What is the effect of VAP CPGs implemented by a multidisciplinary behaviour change strategy (consisting of multifaceted educational strategies led by local opinion leaders and augmented with reminders) on VAP guideline concordance and on clinical VAP outcomes in the ICU? Research Plan: Data will only be collected on consecutive patients mechanically ventilated for at least 48 hours. The following health care professionals will be studied to assess the behaviour change strategy for the VAP CPGs: physicians (intensivists, ICU fellows, ICU rotating residents), nurses, respiratory therapists, dieticians, physiotherapists and ICU administrators. The study will be conducted in 3 phases: 1. Development of a behaviour change strategy consisting of three components: - Local opinion leader team - Educational strategy - Reminder system 2. Prospective implementation of the behaviour change strategy over a 24 month period 3. Prospective evaluation of the behaviour change strategy over a 24 month period - Concordance with VAP guidelines over time - Factors associated with VAP guideline concordance - Clinical VAP outcomes pre- and post-guideline implementation
linkedct:download_date Information obtained from ClinicalTrials.gov on December 30, 2009
linkedct:eligibility_gender Both
linkedct:eligibility_healthy_volunteers No
linkedct:eligibility_maximum_age N/A
linkedct:eligibility_minimum_age 17 Years
linkedct:eligibility_sampling_method Probability Sample
linkedct:eligibility_study_pop Patients invasively mechanically ventilated > 48 hours in the critical care setting.
linkedct:end_date January 2010
linkedct:enrollment 1650 (xsd:int)
linkedct:firstreceived_date February 12, 2007
linkedct:has_dmc No
linkedct:id NCT00434460
linkedct:intervention <http://static.linkedct.org/resource/intervention/40328>
rdfs:label Trial NCT00434460
linkedct:lastchanged_date September 15, 2008
linkedct:lead_sponsor_agency Canadian Critical Care Trials Group
linkedct:location <http://static.linkedct.org/resource/location/15611>
linkedct:location <http://static.linkedct.org/resource/location/159077>
linkedct:location <http://static.linkedct.org/resource/location/18692>
linkedct:location <http://static.linkedct.org/resource/location/18905>
linkedct:location <http://static.linkedct.org/resource/location/19828>
linkedct:location <http://static.linkedct.org/resource/location/20174>
linkedct:location <http://static.linkedct.org/resource/location/20974>
linkedct:location <http://static.linkedct.org/resource/location/21568>
linkedct:location <http://static.linkedct.org/resource/location/22750>
linkedct:location <http://static.linkedct.org/resource/location/23214>
linkedct:location <http://static.linkedct.org/resource/location/23302>
linkedct:nct_id NCT00434460
linkedct:number_of_arms 0 (xsd:int)
linkedct:number_of_groups 1 (xsd:int)
linkedct:official_title Active Observational Study of the Adoption and Transfer of Clinical Practice Guidelines Through Education, for Ventilator Associated Pneumonia (ABATE VAP Study)
linkedct:org_study_id ABATE VAP
linkedct:overall_contact_email muscedej@kgh.kari.net
linkedct:overall_contact_last_name John Muscedere, MD
linkedct:overall_contact_phone 613-549-6666
linkedct:overall_contact_phone_ext 4847
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/11713>
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/13278>
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/29217>
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/32912>
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/35741>
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/46581>
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/49164>
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/53471>
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/57574>
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/6471>
linkedct:overall_status Recruiting
linkedct:oversight <http://static.linkedct.org/resource/oversight/402>
linkedct:oversight <http://static.linkedct.org/resource/oversight/411>
foaf:page <http://clinicaltrials.gov/show/NCT00434460>
linkedct:phase N/A
linkedct:source Canadian Critical Care Trials Group
linkedct:start_date April 2007
linkedct:study_design Cohort, Prospective
linkedct:study_type Observational
linkedct:summary The purpose of this prospective, multicentre, time-series study is to develop, implement, refine, and evaluate a sustainable behaviour change strategy in the intensive care unit (ICU).
rdf:type linkedct:trials
linkedct:verification_date September 2008