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Trial NCT00000177

Resource URI: http://static.linkedct.org/resource/trials/NCT00000177
PropertyValue
linkedct:brief_title Estrogen Hormone Protocol
linkedct:condition <http://static.linkedct.org/resource/condition/829>
linkedct:criteria Inclusion Criteria: - Women with a diagnosis of Alzheimer's disease who currently are not taking estrogen replacement therapy, who have had a hysterectomy, and who are in stable general health. Exclusion Criteria: - Patients with an uncontrolled health problem, such as untreated high blood pressure or thyroid disease.
linkedct:download_date Information obtained from ClinicalTrials.gov on December 30, 2009
linkedct:eligibility_gender Female
linkedct:eligibility_healthy_volunteers No
linkedct:eligibility_maximum_age N/A
linkedct:eligibility_minimum_age 60 Years
linkedct:end_date January 1999
linkedct:enrollment 120 (xsd:int)
linkedct:firstreceived_date October 29, 1999
linkedct:id NCT00000177
rdfs:label Trial NCT00000177
linkedct:lastchanged_date December 10, 2009
linkedct:lead_sponsor_agency National Institute on Aging (NIA)
linkedct:location <http://static.linkedct.org/resource/location/137012>
linkedct:location <http://static.linkedct.org/resource/location/147472>
linkedct:location <http://static.linkedct.org/resource/location/153094>
linkedct:location <http://static.linkedct.org/resource/location/153772>
linkedct:location <http://static.linkedct.org/resource/location/154764>
linkedct:location <http://static.linkedct.org/resource/location/155052>
linkedct:location <http://static.linkedct.org/resource/location/157873>
linkedct:location <http://static.linkedct.org/resource/location/160181>
linkedct:location <http://static.linkedct.org/resource/location/163294>
linkedct:location <http://static.linkedct.org/resource/location/170541>
linkedct:location <http://static.linkedct.org/resource/location/171858>
linkedct:location <http://static.linkedct.org/resource/location/177909>
linkedct:location <http://static.linkedct.org/resource/location/181233>
linkedct:location <http://static.linkedct.org/resource/location/182698>
linkedct:location <http://static.linkedct.org/resource/location/184963>
linkedct:location <http://static.linkedct.org/resource/location/190347>
linkedct:location <http://static.linkedct.org/resource/location/190480>
linkedct:location <http://static.linkedct.org/resource/location/192741>
linkedct:location <http://static.linkedct.org/resource/location/193875>
linkedct:location <http://static.linkedct.org/resource/location/194482>
linkedct:location <http://static.linkedct.org/resource/location/195834>
linkedct:location <http://static.linkedct.org/resource/location/200325>
linkedct:location <http://static.linkedct.org/resource/location/201815>
linkedct:location <http://static.linkedct.org/resource/location/213227>
linkedct:location <http://static.linkedct.org/resource/location/220436>
linkedct:nct_id NCT00000177
linkedct:number_of_arms 0 (xsd:int)
linkedct:number_of_groups 0 (xsd:int)
linkedct:org_study_id IA0001
linkedct:overall_official <http://static.linkedct.org/resource/overall_official/34878>
linkedct:overall_status Completed
linkedct:oversight <http://static.linkedct.org/resource/oversight/2918>
foaf:page <http://clinicaltrials.gov/show/NCT00000177>
linkedct:phase Phase 3
linkedct:primary_completion_date January 1999
linkedct:results_reference <http://static.linkedct.org/resource/results_reference/2194>
linkedct:secondary_id 3U01AG10483-08S2
linkedct:source National Institute on Aging (NIA)
linkedct:start_date October 1995
linkedct:study_design Treatment, Randomized, Double-Blind, Placebo Control
linkedct:study_type Interventional
linkedct:summary Estrogen is a hormone that is dominant in the female reproductive system. In women, most estrogen is produced by the ovaries. Men produce estrogen by converting testosterone into estrogen. Because this hormone also has many beneficial effects on brain cells, it currently is being studied as a treatment for Alzheimer's disease. The enzyme that forms the neurotransmitter acetylcholine is promoted in the presence of estrogen. Several very small clinical studies have demonstrated improvement in cognitive function and mood measures in women with Alzheimer's disease who take estrogen.
rdf:type linkedct:trials
linkedct:verification_date September 2009