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Trial NCT00000110

Resource URI: http://static.linkedct.org/resource/trials/NCT00000110
linkedct:brief_title Influence of Diet and Endurance Running on Intramuscular Lipids Measured at 4.1 TESLA
linkedct:condition <http://static.linkedct.org/resource/condition/9106>
linkedct:criteria Inclusion Criteria: - Healthy volunteers (developmental phase) - Healthy endurance-trained subjects - Maximum age for males is 39 - Maximum age for females is 49
linkedct:download_date Information obtained from ClinicalTrials.gov on December 30, 2009
linkedct:eligibility_gender Both
linkedct:eligibility_healthy_volunteers Accepts Healthy Volunteers
linkedct:eligibility_maximum_age 49 Years
linkedct:eligibility_minimum_age 18 Years
linkedct:enrollment 0 (xsd:int)
linkedct:firstreceived_date January 18, 2000
linkedct:id NCT00000110
rdfs:label Trial NCT00000110
linkedct:lastchanged_date June 23, 2005
linkedct:lead_sponsor_agency National Center for Research Resources (NCRR)
linkedct:location <http://static.linkedct.org/resource/location/177811>
linkedct:nct_id NCT00000110
linkedct:number_of_arms 0 (xsd:int)
linkedct:number_of_groups 0 (xsd:int)
linkedct:org_study_id NCRR-M01RR00032-0855
linkedct:overall_status Completed
linkedct:oversight <http://static.linkedct.org/resource/oversight/2918>
foaf:page <http://clinicaltrials.gov/show/NCT00000110>
linkedct:phase N/A
linkedct:secondary_id M01RR00032
linkedct:source National Center for Research Resources (NCRR)
linkedct:study_design Treatment, Single Blind
linkedct:study_type Interventional
linkedct:summary The purpose of this pilot investigation is to use 1 H Magnetic Resonance Spectroscopy (MRS) to 1) document the change in intra-muscular lipid stores (IML) before and after a prolonged bout of endurance running and, 2) determine the pattern (time course) of IML replenishment following an extremely low-fat diet (10% of energy from fat) and a moderate-fat diet (35% of energy from fat). Specifically, the study will evaluate the change in IML following a 2-hour training run and the recovery of IML in response to the post-exercise low-fat or moderate-fat diet in 10 endurance trained athletes who will consume both diets in a randomly assigned cross-over fashion. We hypothesize that IML will be depleted with prolonged endurance exercise, and that replenishment of IML will be impaired by an extremely low-fat diet compared to a moderate-fat diet. Results of this pilot study will be used to apply for extramural grant support from NIH or the US Armed Forces to investigate the effect of dietary fat on the health and performance of individuals performing heavy physical training. It is anticipated that this methodology could also be employed in obesity research to delineate, longitudinally, the reported cross-sectional relationships among IML stores, insulin resistance and obesity.
rdf:type linkedct:trials
linkedct:verification_date December 2003