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Intervention #100059 (Drug:oral topotecan (SK&F-104864); lapatinib (GW572016))

Resource URI: http://static.linkedct.org/resource/intervention/100059
linkedct:description This is a single-arm, dose escalation, Phase I study in which doses of oral topotecan will be escalated and lapatinib will be given initially as a fixed dose. This study will examine oral topotecan administered on a five-consecutive day schedule in combination with daily lapatinib. This study will be conducted in two parts. Part 1 of the study will investigate the impact of lapatinib on the bioavailability of oral topotecan (bioavailability phase) and Part 2 of the study will consist of dose finding to determine the MTD regimen of the combination (dose escalation phase).
is linkedct:intervention of <http://static.linkedct.org/resource/trials/NCT00682279>
linkedct:intervention_id 100059 (xsd:int)
linkedct:intervention_name oral topotecan (SK&F-104864); lapatinib (GW572016)
linkedct:intervention_type Drug
rdfs:label Intervention #100059 (Drug:oral topotecan (SK&F-104864); lapatinib (GW572016))
rdf:type linkedct:intervention